Packet 6: Bonus 7
CELSR1 is an atypical one of these proteins, whose E-type binds to beta-catenin via their cytoplasmic tails. For 10 points each:
[10m] Name these type-1 transmembrane proteins that rely on a certain element for their function. These proteins’ desmosomal type include desmogleins (“DEZ-mo-gleens”), which are targeted in the autoimmune disease pemphigus vulgaris.
ANSWER: cadherins
[10e] Extracellular binding domains for this element allow cadherins to maintain cytoskeletal structure. This element’s divalent cation is stored in the sarcoplasmic reticulum.
ANSWER: calcium [or Ca; accept Ca2+ or divalent calcium]
[10h] Expression of E-cadherin and nectin-2-alpha leads to the recruitment of this complex to cell junctions in fibroblasts. This complex is responsible for regulating vesicle delivery.
ANSWER: sec6/8 complex [or exocyst]
<British Columbia, Biology> | F. Prelims 6 - British Columbia + Texas + North Carolina
| Heard | PPB | E % | M % | H % |
|---|---|---|---|---|
| 21 | 12.86 | 91% | 38% | 0% |
Conversion
| Team | Opponent | Part 1 | Part 2 | Part 3 | Total | Parts |
|---|---|---|---|---|---|---|
| Brown | Northwestern B | 10 | 10 | 0 | 20 | ME |
| Columbia B | Waterloo | 0 | 10 | 0 | 10 | E |
| Georgetown | WashU | 0 | 0 | 0 | 0 | |
| Georgia Tech A | Harvard | 10 | 10 | 0 | 20 | ME |
| Georgia Tech B | Purdue | 10 | 10 | 0 | 20 | ME |
| Illinois B | Bruin | 0 | 10 | 0 | 10 | E |
| Indiana | Cornell | 0 | 10 | 0 | 10 | E |
| Johns Hopkins | Illinois A | 10 | 10 | 0 | 20 | ME |
| MIT | NYU B | 0 | 10 | 0 | 10 | E |
| Minnesota | UCLA | 0 | 10 | 0 | 10 | E |
| NYU A | UC Berkeley B | 0 | 10 | 0 | 10 | E |
| Northwestern A | Chicago B | 10 | 10 | 0 | 20 | ME |
| Penn State | Maryland B | 0 | 10 | 0 | 10 | E |
| Rutgers | Columbia A | 0 | 10 | 0 | 10 | E |
| Stanford A | Georgia Tech C | 10 | 10 | 0 | 20 | ME |
| Stanford B | Vanderbilt | 0 | 0 | 0 | 0 | |
| Swarthmore | Chicago A | 0 | 10 | 0 | 10 | E |
| Toronto B | Michigan | 10 | 10 | 0 | 20 | ME |
| UC Berkeley A | Cambridge | 10 | 10 | 0 | 20 | ME |
| Virginia | UCF | 0 | 10 | 0 | 10 | E |
| Virginia Tech | Toronto A | 0 | 10 | 0 | 10 | E |
Summary
| Tournament | Edition | Match | Heard | PPB | E % | M % | H % |
|---|---|---|---|---|---|---|---|
| Main Site | 2026-04-17 | ✓ | 21 | 12.86 | 91% | 38% | 0% |