Packet 4: Bonus 5

Drugs encased in these non-micelle structures are PEGylated (“PEG-uh-lated”) to allow permeation of the blood–brain barrier. For 10 points each:
[10e] Name these structures whose diameter is about 9 orders of magnitude smaller than a meter.
ANSWER: nanoparticles [accept lipid nanoparticles]
[10h] In 2011, Sotiriou et al. coated these nanoparticles in silica to make them biocompatible for drug delivery. These nanoparticles, which are used to stabilize Pickering emulsions, have unique surface chemistry that allow them to undergo two different reactions at once.
ANSWER: Janus particles [accept Janus-like particles]
[10m] In drug discovery, this assay can measure the binding efficiency and thin-film thickness of an adsorbed nanoparticle. This assay is named for an effect in which light excites electrons on a metal sheet, where binding of the analyte causes a change in refractive index.
ANSWER: surface plasmon resonance assay [or SPR; accept localized surface plasmon resonance or multiparametric surface plasmon resonance or LSPR or MP-SPR; prompt on resonance or surface resonance]
<Editors, Chemistry> | D. Prelims 4 - Toronto B + Harvard + Michigan + Minnesota

HeardPPBE %M %H %
217.6238%29%10%

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Conversion

TeamOpponentPart 1Part 2Part 3TotalParts
British ColumbiaColumbia A1001020EM
BrownJohns Hopkins100010E
BruinChicago B0000
CambridgeUCF1001020EM
Georgia Tech BPenn State0000
Georgia Tech CIllinois B0000
Illinois ANorthwestern B0000
MITWaterloo100010E
Maryland ACornell0000
NYU AVanderbilt0000
NYU BColumbia B100010E
Northwestern AStanford A1001020EM
Ohio StateGeorgetown1001020EM
PittsburghIndiana100010E
SwarthmoreGeorgia Tech A010010H
UC Berkeley ANorth Carolina001010M
UC Berkeley BStanford B010010H
UCLAToronto A001010M
VirginiaRutgers0000
Virginia TechMaryland B0000
WashUTexas0000

Summary

TournamentEditionMatchHeardPPBE %M %H %
Main Site2026-04-17✓217.6238%29%10%