Packet 9: Bonus 19
The D1 subtype of these proteins is aberrantly expressed in some forms of mantle cell lymphoma. For 10 points each:
[10m] Name these proteins with oscillating expression over the cell cycle. They were originally discovered by Tim Hunt in sea urchins.
ANSWER: cyclins
[10e] Cyclin B is degraded at the onset of this phase. This mitotic stage begins when securin is degraded to free separase, which in turn cleaves cohesin so that sister chromatids move poleward.
ANSWER: anaphase
[10h] This tyrosine kinase, which was discovered from a “small” S. pombe phenotype, inhibits Cdk1 by phosphorylating Tyr15 and preventing entry into mitosis. The action of this kinase is opposed by Cdc25.
ANSWER: Wee1 kinase
<Editors, Biology> | R. Playoffs 9 (Editors 9)
| Heard | PPB | E % | M % | H % |
|---|---|---|---|---|
| 10 | 17.00 | 90% | 80% | 0% |
Conversion
| Team | Opponent | Part 1 | Part 2 | Part 3 | Total | Parts |
|---|---|---|---|---|---|---|
| Columbia B | Ohio State | 0 | 10 | 0 | 10 | E |
| Harvard | Indiana | 10 | 10 | 0 | 20 | ME |
| Johns Hopkins | Michigan | 10 | 10 | 0 | 20 | ME |
| NYU A | Northwestern A | 0 | 10 | 0 | 10 | E |
| Pittsburgh | UCLA | 10 | 10 | 0 | 20 | ME |
| Purdue | Cornell | 10 | 10 | 0 | 20 | ME |
| Swarthmore | Waterloo | 10 | 10 | 0 | 20 | ME |
| Texas | MIT | 10 | 0 | 0 | 10 | M |
| Toronto A | UC Berkeley B | 10 | 10 | 0 | 20 | ME |
| UCF | Georgetown | 10 | 10 | 0 | 20 | ME |
Summary
| Tournament | Edition | Match | Heard | PPB | E % | M % | H % |
|---|---|---|---|---|---|---|---|
| Main Site | 2026-04-17 | ✓ | 10 | 17.00 | 90% | 80% | 0% |