Packet 1: Bonus 1
One of these proteins called macroH2A has an additional 30 kilodalton domain and only appears in inactivated X chromosomes. For 10 points each:
[10e] Name these positively-charged proteins that form octamers called nucleosomes. DNA wraps around these proteins to form chromatin.
ANSWER: histones
[10m] This method crosslinks DNA–protein complexes, fragments chromatin by sonication or MNase, and uses an antibody to pull down specific histone marks. It is usually followed by sequencing or qPCR.
ANSWER: ChIP-seq [or chromatin immunoprecipitation-sequencing; prompt on IP or immunoprecipitation]
[10h] This family of histone acetyltransferases is mutated in Rubinstein–Taybi syndrome. This family has a bromodomain, PHD finger, and a KIX (“kicks”) domain that interacts with MYB and CREB.
ANSWER: p300 [accept EP300 or E1A or CBP or CREB-binding protein or CREBBP]
<Editors, Biology> | U. Finals 1 (Editors 11)
| Heard | PPB | E % | M % | H % |
|---|---|---|---|---|
| 1 | 10.00 | 100% | 0% | 0% |
Conversion
| Team | Opponent | Part 1 | Part 2 | Part 3 | Total | Parts |
|---|---|---|---|---|---|---|
| Chicago A | Stanford A | 10 | 0 | 0 | 10 | E |
Summary
| Tournament | Edition | Match | Heard | PPB | E % | M % | H % |
|---|---|---|---|---|---|---|---|
| Main Site | 2026-04-17 | ✓ | 1 | 10.00 | 100% | 0% | 0% |