Packet 1: Bonus 12
In the presence of acetic acid, this compound cyclizes into an oxazolone in the first step of the Erlenmeyer amino acid synthesis. For 10 points each:
[10h] Name this carboxylic acid metabolite found in urine that indicates toluene toxicity when in high concentration. A para-amino derivative of this compound can be used to test blood flow through the kidneys.
ANSWER: hippuric acid [or hippurate; accept benzamidoacetic acid or benzoyl amidoacetic acid; accept para-aminohippuric acid or PAH]
[10e] Toluene is converted to hippuric acid during metabolism by reacting it with this amino acid. This achiral (“ay-KYE-rull”) amino acid has a hydrogen side-chain.
ANSWER: glycine [or Gly or G]
[10m] The first step of toluene metabolism is one of these reactions catalyzed by cytochrome P450 enzymes. This reaction is the rate limiting step of serotonin synthesis from tryptophan, and converts tyrosine to L-DOPA.
ANSWER: hydroxylation [accept tyrosine hydroxylase; prompt on oxidations; prompt on monooxygenations by asking “what transformation does that reaction cause?”]
<Editors, Chemistry> | U. Finals 1 (Editors 11)
| Heard | PPB | E % | M % | H % |
|---|---|---|---|---|
| 1 | 20.00 | 100% | 100% | 0% |
Conversion
| Team | Opponent | Part 1 | Part 2 | Part 3 | Total | Parts |
|---|---|---|---|---|---|---|
| Chicago A | Stanford A | 0 | 10 | 10 | 20 | EM |
Summary
| Tournament | Edition | Match | Heard | PPB | E % | M % | H % |
|---|---|---|---|---|---|---|---|
| Main Site | 2026-04-17 | ✓ | 1 | 20.00 | 100% | 100% | 0% |